Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 18/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509449 | 0.77 | MEN1 (0.43) | MEN1KMT2AREN | |
| SCHEMBL5503829 | 0.77 | REN (0.52) | REN | |
| SCHEMBL5509831 | 0.77 | REN (0.52) | REN | |
| SCHEMBL1865703 | 0.77 | REN (0.52) | REN | |
| SCHEMBL1866281 | 0.77 | REN (0.52) | REN | |
| SCHEMBL5505418 | 0.77 | MEN1 (0.43) | MEN1KMT2AREN | |
| SCHEMBL5505794 | 0.77 | REN (0.52) | REN | |
| SCHEMBL5503748 | 0.71 | DPP4 (0.39) | MEN1KMT2A | |
| SCHEMBL1860871 | 0.71 | DPP4 (0.52) | REN | |
| SCHEMBL1860867 | 0.71 | DPP4 (0.52) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807078-A1 | DIAMINOALKANE ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006042150-A1 | DIAMINOALKANE ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2006-04-20 | — | — | WO | disclosed |