SCHEMBL5503898

SCHEMBL5503898

CCCCC(CC)CC1(CC(CC)CCCC)c2cc(-c3ccc4c(c3)C(CCC)(CCC)c3cc(-c5ccc6c(c5)C(CCC)(CCC)c5ccccc5-6)ccc3-4)ccc2-c2ccc([Si](C)(C)C)cc21

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PDK2 Q15119 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5502936 0.92 MEN1 (0.38) MEN1MAPTKMT2AL3MBTL1PDK2
SCHEMBL5501660 0.85 MEN1 (0.34) MEN1MAPTKMT2AL3MBTL1
SCHEMBL5663449 0.85
SCHEMBL5498599 0.85 PDK2 (0.32) PDK2
SCHEMBL5499782 0.80 SMN1; SMN2 (0.30)
SCHEMBL5502649 0.79 MEN1 (0.31) MEN1MAPTKMT2AL3MBTL1
SCHEMBL6353229 0.79 MMP12 (0.38) MEN1MAPTKMT2AL3MBTL1PDK2
SCHEMBL3721035 0.78 L3MBTL1 (0.46) MEN1MAPTKMT2AL3MBTL1PDK2
SCHEMBL29377775 0.78 L3MBTL1 (0.46) MEN1MAPTKMT2AL3MBTL1PDK2
SCHEMBL13607204 0.78 MEN1 (0.37) MEN1MAPTKMT2AL3MBTL1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1527873-B1 Multilayers of polyamide/polyurethane for decorated articles ARKEMA FRANCE (FR) 2019-08-21 EP disclosed
EP-1765590-A1 POLYAMIDE-BASED MULTI-LAYER STRUCTURE WHICH IS USED TO COVER SUBSTRATES Arkema France (FR) 2007-03-28 EP disclosed
EP-1425168-A4 LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS UNIV ROCHESTER (US) 2007-01-03 EP disclosed
US-7057009-B2 Crosslinking polyfluorene; molecular orientation UNIVERSITY OF ROCHESTER (US) 2006-06-06 US disclosed
WO-2006008357-A1 POLYAMIDE-BASED MULTI-LAYER STRUCTURE WHICH IS USED TO COVER SUBSTRATES ARKEMA FRANCE (FR) 2006-01-26 WO disclosed
EP-1559543-A2 Multilayer structures for decorated articles : polyamide 1 / intermediate layer / polyamide 2 Arkema (FR) 2005-08-03 EP disclosed
EP-1527873-A1 Multilayers of polyamide/polyurethane for decorated articles ARKEMA (FR) 2005-05-04 EP disclosed
EP-1470189-A1 ANTISTATIC STRENIQUE POLYMER COMPOSITIONS Atofina (FR) 2004-10-27 EP disclosed
EP-1470188-A1 ANTISTATIC STYRENIC POLYMER COMPOSITION Atofina (FR) 2004-10-27 EP disclosed
EP-1425168-A2 LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS University of Rochester (US) 2004-06-09 EP disclosed
WO-2003068860-A1 ANTISTATIC STYRENIC POLYMER COMPOSITION ATOFINA (FR) 2003-08-21 WO disclosed
WO-2003068861-A1 ANTISTATIC STRENIQUE POLYMER COMPOSITIONS ATOFINA (FR) 2003-08-21 WO disclosed
US-20030039838-A1 Light-emitting organic oligomer compositions UNIVERSITY OF ROCHESTER 2003-02-27 US disclosed
WO-2003008475-A2 LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS UNIVERSITY OF ROCHESTER (US) 2003-01-30 WO disclosed
EP-1167439-A1 Impact-resistant blends of vinyl aromatic resin and polyphenylene ether Atofina (FR) 2002-01-02 EP disclosed
EP-1121391-A1 ANTISTATIC STYRENE POLYMER COMPOSITIONS Atofina (FR) 2001-08-08 EP disclosed
WO-2001010951-A1 ANTISTATIC STYRENE POLYMER COMPOSITIONS ATOFINA (FR) 2001-02-15 WO disclosed