Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD3 | Q99594 | 2/20 | 0.50 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19600932 | 0.81 | HTT (0.49) | STSGPR119JAK2JAK1KDM4E | |
| SCHEMBL3779080 | 0.80 | CHRM4 (0.56) | STSGPR119KDM4EPKMTHRB | |
| SCHEMBL25326370 | 0.80 | TEAD3 (0.56) | TEAD3STSKDM4EGAAMEN1 | |
| SCHEMBL119649 | 0.79 | SMN1; SMN2 (0.58) | STSGPR119JAK2JAK1KDM4E | |
| SCHEMBL310136 | 0.79 | SMN1; SMN2 (0.58) | STSGPR119JAK2JAK1KDM4E | |
| Hydrochloric Acid SCHEMBL3966170 | 0.79 | CHRM4 (0.55) | STSGPR119KDM4ETHRBSMN1; SMN2 | |
| SCHEMBL3251863 | 0.79 | KDM4E (0.58) | STSGPR119JAK2JAK1KDM4E | |
| SCHEMBL31303428 | 0.78 | STS (0.52) | TEAD3STSGPR119JAK2JAK1 | |
| SCHEMBL13096781 | 0.78 | STS (0.52) | TEAD3STSGPR119JAK2JAK1 | |
| SCHEMBL5506815 | 0.78 | RECQL (0.40) | GPR119SMN1; SMN2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |