Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5504095 | 0.78 | TEAD3 (0.50) | GPR119SMN1; SMN2EPHX2 | |
| SCHEMBL4214378 | 0.76 | GPR119 (0.47) | RECQLHPGDFAAHGPR119USP2 | |
| SCHEMBL4224647 | 0.75 | RECQL (0.45) | RECQLHPGDFAAHGPR119USP2 | |
| SCHEMBL4388977 | 0.75 | TP53 (0.42) | RECQLHPGDFAAHGPR119GLS | |
| SCHEMBL5507425 | 0.74 | HPGD (0.43) | RECQLHPGDGPR119EPHX1 | |
| SCHEMBL5109520 | 0.73 | GPR119 (0.48) | RECQLHPGDFAAHGPR119USP2 | |
| SCHEMBL24745481 | 0.73 | HPGD (0.46) | RECQLHPGDGPR119USP2SMN1; SMN2 | |
| SCHEMBL1795814 | 0.73 | HPGD (0.46) | RECQLHPGDGPR119USP2SMN1; SMN2 | |
| SCHEMBL30150917 | 0.73 | ACACB (0.38) | GPR119USP2SMN1; SMN2EPHX2 | |
| SCHEMBL30150918 | 0.73 | ACACB (0.38) | GPR119USP2SMN1; SMN2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |