Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.56 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6289374 | 0.87 | PTGDR2 (0.55) | PTGDR2P2RY1LMNABRD4HDAC1 | |
| SCHEMBL6648773 | 0.80 | NPSR1 (0.61) | PTGDR2LMNABRD4HDAC1HDAC7 | |
| SCHEMBL5503246 | 0.79 | PTGDR2 (0.59) | PTGDR2P2RY1LMNASMN1; SMN2 | |
| SCHEMBL4123305 | 0.79 | PTGDR2 (0.59) | PTGDR2P2RY1LMNASMN1; SMN2 | |
| SCHEMBL4123301 | 0.79 | PTGDR2 (0.59) | PTGDR2P2RY1LMNASMN1; SMN2 | |
| SCHEMBL4123726 | 0.78 | PTGDR2 (0.80) | PTGDR2 | |
| SCHEMBL6281754 | 0.77 | PTGDR2 (0.56) | PTGDR2P2RY1LMNASMN1; SMN2 | |
| SCHEMBL4127033 | 0.77 | PTGDR2 (0.56) | PTGDR2P2RY1LMNASMN1; SMN2 | |
| SCHEMBL27622502 | 0.77 | PTGDR2 (0.56) | PTGDR2LMNASMN1; SMN2 | |
| SCHEMBL4116661 | 0.76 | PTGDR2 (0.65) | PTGDR2P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740547-A1 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005100321-A1 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-10-27 | — | — | WO | disclosed |