Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5504206 | 1.00 | MEN1 (0.62) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL2229690 | 0.86 | MEN1 (0.66) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL27655716 | 0.84 | MEN1 (0.74) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL8330995 | 0.83 | MEN1 (0.62) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL9789402 | 0.83 | MEN1 (0.62) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL20596721 | 0.83 | MCL1 (0.45) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL9716955 | 0.82 | ALDH1A1 (0.51) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL6388241 | 0.81 | MEN1 (0.65) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL8408159 | 0.81 | MEN1 (0.65) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL7672337 | 0.80 | ABCG2 (0.51) | MEN1KMT2AALDH1A1MCL1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814866-A2 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2007-08-08 | — | — | EP | claimed |
| WO-2006058012-A2 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS | WYETH (US) | 2006-06-01 | — | — | WO | claimed |