Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL538804 | 0.88 | LMNA (0.54) | ALDH1A1LMNATSHRKDM4EPOLB | |
| SCHEMBL8092299 | 0.88 | LMNA (0.54) | ALDH1A1LMNATSHRKDM4EPOLB | |
| SCHEMBL5176548 | 0.88 | LMNA (0.54) | ALDH1A1LMNATSHRKDM4EPOLB | |
| SCHEMBL10350181 | 0.88 | LMNA (0.54) | ALDH1A1LMNATSHRKDM4EPOLB | |
| SCHEMBL10497654 | 0.86 | CES2 (0.51) | ALDH1A1LMNATSHRKDM4EPOLB | |
| SCHEMBL27946955 | 0.84 | CES2 (0.50) | ALDH1A1LMNATSHRKDM4EPOLB | |
| SCHEMBL27636742 | 0.83 | TSHR (0.49) | ALDH1A1LMNATSHRKDM4EPOLB | |
| SCHEMBL8154501 | 0.82 | TSHR (0.48) | ALDH1A1LMNATSHRKDM4EPOLB | |
| SCHEMBL5549124 | 0.82 | LMNA (0.46) | ALDH1A1LMNATSHRKDM4EPOLB | |
| SCHEMBL5078093 | 0.82 | TDP1 (0.51) | ALDH1A1LMNATSHRKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992009561-A1 | NEW AMIDE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-06-11 | — | — | WO | disclosed |