Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4463002 | 0.88 | F10 (0.48) | F10 | |
| SCHEMBL4471621 | 0.84 | F10 (0.55) | F10MAPTLMNATP53POLB | |
| SCHEMBL4462995 | 0.82 | F10 (0.72) | F10 | |
| SCHEMBL4004646 | 0.80 | F10 (0.64) | F10 | |
| SCHEMBL4465206 | 0.76 | F10 (0.67) | F10 | |
| SCHEMBL5503901 | 0.74 | F10 (0.60) | F10 | |
| SCHEMBL4473755 | 0.74 | F10 (0.55) | F10 | |
| SCHEMBL4478016 | 0.73 | F10 (0.50) | F10 | |
| SCHEMBL4463010 | 0.73 | F10 (0.51) | F10 | |
| SCHEMBL8337162 | 0.72 | ALDH1A1 (0.49) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101014591-A | Novel substituted thiophenecarboxamides, process for their preparation and their use as medicaments | BOEHRINGER INGELHEIM INT (DE) | 2007-08-08 | — | — | CN | disclosed |
| EP-1747217-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005111029-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |