Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | TGM1 | P22735 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | SORD | Q00796 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2156392 | 0.74 | KDM4E (0.55) | KDM4EALDH1A1MAPTHSD17B10CTSS | |
| SCHEMBL7363493 | 0.74 | KDM4E (0.52) | KDM4EALDH1A1MAPTHSD17B10CTSS | |
| SCHEMBL12463845 | 0.73 | KDM4E (0.56) | KDM4EALDH1A1MAPTHSD17B10CTSS | |
| SCHEMBL2155256 | 0.72 | KDM4E (0.55) | KDM4EALDH1A1MAPTHSD17B10CTSS | |
| SCHEMBL12463849 | 0.72 | MMP7 (0.61) | KDM4EALDH1A1MAPTHSD17B10CTSS | |
| SCHEMBL2155302 | 0.72 | KDM4E (0.54) | KDM4EALDH1A1MAPTHSD17B10CTSS | |
| SCHEMBL2155000 | 0.72 | KDM4E (0.51) | KDM4EALDH1A1MAPTHSD17B10CTSS | |
| SCHEMBL2155157 | 0.70 | KDM4E (0.52) | KDM4EALDH1A1MAPTHSD17B10CTSS | |
| SCHEMBL14252763 | 0.70 | MMP7 (0.61) | KDM4EALDH1A1MAPTHSD17B10CTSS | |
| SCHEMBL4816679 | 0.70 | MMP7 (0.61) | KDM4EALDH1A1MAPTHSD17B10CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828160-A1 | SULFONYL AMINO CYCLIC DERIVATIVES AND USE THEREOF AS MMP INHIBITORS | LABORATOIRES SERONO S.A. (CH) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006067114-A1 | SULFONYL AMINO CYCLIC DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2006-06-29 | — | — | WO | disclosed |