Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.41 |
| ▸ | CMA1 | P23946 | 2/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.41 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.41 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2491904 | 0.80 | AHR (0.50) | AHRCMA1GRIA1CACNG8EIF2AK2 | |
| SCHEMBL2486755 | 0.77 | GRIA1 (0.51) | AHRCMA1GRIA1CACNG8EIF2AK2 | |
| SCHEMBL12415678 | 0.77 | AHR (0.53) | AHRCMA1GRIA1CACNG8EIF2AK2 | |
| SCHEMBL12056356 | 0.77 | AHR (0.41) | AHRCMA1GRIA1CACNG8EIF2AK2 | |
| SCHEMBL5499132 | 0.75 | PGR (0.43) | AHRCMA1GRIA1CACNG8EIF2AK2 | |
| SCHEMBL5499457 | 0.75 | AHR (0.42) | AHRCMA1GRIA1CACNG8EIF2AK2 | |
| SCHEMBL11106607 | 0.74 | AHR (0.53) | AHRCMA1GRIA1CACNG8EIF2AK2 | |
| SCHEMBL13619932 | 0.73 | SRC (0.46) | AHRCMA1GRIA1CACNG8EIF2AK2 | |
| SCHEMBL4660496 | 0.73 | AHR (0.41) | AHRCMA1GRIA1CACNG8EIF2AK2 | |
| SCHEMBL31010750 | 0.73 | AHR (0.59) | AHRCMA1GRIA1CACNG8EIF2AK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781642-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016221-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |