Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.60 |
| ▸ | RAF1 | P04049 | 2/20 | 0.47 |
| ▸ | BRAF | P15056 | 2/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4000970 | 0.88 | F10 (0.66) | F10RAF1BRAFCNR2 | |
| SCHEMBL29653575 | 0.84 | F10 (0.62) | F10RAF1BRAFCNR2 | |
| SCHEMBL5217814 | 0.82 | F10 (0.59) | F10 | |
| SCHEMBL4465409 | 0.82 | F10 (0.59) | F10 | |
| SCHEMBL5508172 | 0.81 | F10 (0.59) | F10 | |
| SCHEMBL27691847 | 0.81 | F10 (0.61) | F10 | |
| SCHEMBL4476742 | 0.81 | F10 (0.79) | F10 | |
| SCHEMBL5503901 | 0.80 | F10 (0.60) | F10 | |
| SCHEMBL1377777 | 0.80 | F10 (0.58) | F10RAF1BRAF | |
| SCHEMBL1377268 | 0.79 | F10 (0.55) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747217-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005111029-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |