SCHEMBL5504467

SCHEMBL5504467

CN1CCc2ccc(OCCCN3CCN(c4cccc5sccc45)CC3)cc2C1

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 3/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5512064 0.90 DRD2 (0.67) DRD2
SCHEMBL24312876 0.89 DRD2 (0.65) DRD2
Hydrochloric Acid SCHEMBL293811 0.85 DRD2 (0.62) DRD2
SCHEMBL1037542 0.85 DRD2 (0.68) DRD2
SCHEMBL1039550 0.85 DRD2 (0.71) DRD2
SCHEMBL1038733 0.84 DRD2 (0.87) DRD2
SCHEMBL1037298 0.84 DRD2 (1.00) DRD2
SCHEMBL5508049 0.83 DRD2 (0.71) DRD2
SCHEMBL1037951 0.83 DRD2 (0.64) DRD2
Hydrochloric Acid SCHEMBL1040421 0.83 DRD2 (0.98) DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1869025-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-12-26 EP claimed
WO-2006112464-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-10-26 WO claimed
EP-1869025-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-12-26 EP disclosed
WO-2006112464-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-10-26 WO disclosed