Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.71 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1039550 | 0.96 | DRD2 (0.71) | DRD2HTR1AHTR2AKCNH2 | |
| Hydrochloric Acid SCHEMBL293576 | 0.86 | DRD2 (0.75) | DRD2 | |
| SCHEMBL1036530 | 0.84 | DRD2 (0.72) | DRD2HTR1AHTR2A | |
| SCHEMBL1039789 | 0.84 | DRD2 (0.67) | DRD2HTR1AHTR2A | |
| SCHEMBL1039673 | 0.84 | DRD2 (0.69) | DRD2 | |
| SCHEMBL5504467 | 0.83 | DRD2 (0.72) | DRD2 | |
| SCHEMBL1039707 | 0.83 | DRD2 (1.00) | DRD2 | |
| SCHEMBL1039560 | 0.83 | DRD2 (0.87) | DRD2 | |
| SCHEMBL1038131 | 0.83 | DRD2 (0.70) | DRD2 | |
| Hydrochloric Acid SCHEMBL1034597 | 0.83 | DRD2 (0.68) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869025-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006112464-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-10-26 | — | — | WO | disclosed |