Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.82 |
| ▸ | RAB9A | P51151 | 9/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.82 |
| ▸ | NPC1 | O15118 | 8/20 | 0.82 |
| ▸ | MEN1 | O00255 | 6/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.82 |
| ▸ | HPGD | P15428 | 4/20 | 0.82 |
| ▸ | TP53 | P04637 | 3/20 | 0.82 |
| ▸ | PPARG | P37231 | 2/20 | 0.81 |
| ▸ | PPARD | Q03181 | 2/20 | 0.81 |
| ▸ | PPARA | Q07869 | 2/20 | 0.81 |
| ▸ | XDH | P47989 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.62 |
| ▸ | BCL2 | P10415 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30527861 | 1.00 | MAPT (0.82) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL2069068 | 0.91 | MAPT (0.77) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL7499952 | 0.91 | MAPT (0.77) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL762092 | 0.90 | MAPT (1.00) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL2070726 | 0.90 | PPARG (1.00) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL4366282 | 0.90 | MAPT (0.74) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL3494129 | 0.89 | MAPT (0.73) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL571576 | 0.87 | XDH (0.84) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL30527851 | 0.86 | MAPT (0.70) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL29085509 | 0.86 | MAPT (0.70) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113512018-B | Flavonoid compound and preparation method and application thereof | 合肥工业大学 | 2023-07-18 | — | — | CN | disclosed |
| EP-1778656-A1 | BENZOXAZEPINE DERIVATIVES AS SELECTIVE ESTROGEN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006023242-A1 | BENZOXAZEPINE DERIVATIVES AS SELECTIVE ESTROGEN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-03-02 | — | — | WO | disclosed |
| US-20060040917-A1 | Benzoxazepine derivatives as selective estrogen receptor modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040917-A1 | Benzoxazepine derivatives as selective estrogen receptor modulators | GPER1, ESR2, ESR1 | MAPT 1607/4885SMN1; SMN2 4276/4885RAB9A 3664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.