SCHEMBL762092

SCHEMBL762092

COc1ccc2c(=O)c(-c3ccccc3)coc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 11/20 1.00
▸ ALDH1A1 P00352 10/20 1.00
▸ SMN1; SMN2 Q16637 9/20 1.00
▸ NPC1 O15118 9/20 1.00
▸ RAB9A P51151 9/20 1.00
▸ KDM4E B2RXH2 6/20 1.00
▸ MEN1 O00255 5/20 1.00
▸ KMT2A Q03164 5/20 1.00
▸ TP53 P04637 4/20 1.00
▸ CYP3A4 P08684 4/20 1.00
▸ HPGD P15428 4/20 1.00
▸ PIN1 Q13526 1/20 0.78
▸ XDH P47989 1/20 0.76
▸ MAPK1 P28482 3/20 0.74
▸ HDAC6 Q9UBN7 2/20 0.74
▸ POLB P06746 2/20 0.74
▸ GAA P10253 2/20 0.74
▸ HIF1A Q16665 2/20 0.74
▸ PTGS1 P23219 1/20 0.74
▸ SLC6A2 P23975 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL571576 0.91 XDH (0.84) MAPTALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL30527861 0.90 MAPT (0.82) MAPTALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL5504492 0.90 MAPT (0.82) MAPTALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL29068825 0.89 MAPT (0.80) MAPTALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL1742372 0.88 PIN1 (1.00) MAPTALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL5814089 0.87 XDH (0.78) MAPTALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL13774686 0.86 XDH (0.76) MAPTALDH1A1SMN1; SMN2NPC1RAB9A
Isoformonentin SCHEMBL73338 0.86 XDH (1.00) MAPTALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL12289033 0.86 XDH (0.76) MAPTALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL22340136 0.86 XDH (0.76) MAPTALDH1A1SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4599048-A1 COMPOSITIONS AND METHODS FOR SMALL MOLECULE BASED EXPANSION OF PLURIPOTENT STEM CELLS Trailhead Biosystems Inc. (US) 2025-08-13 — — EP claimed
EP-4569090-A2 METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS Trailhead Biosystems Inc. (US) 2025-06-18 — — EP claimed
CN-119654404-A Methods and compositions for producing oligodendrocyte progenitor cells 特雷尔赫德生物系统股份有限公司 2025-03-18 — — CN claimed
EP-4444870-A1 METHODS AND COMPOSITIONS FOR GENERATING HUMAN ERYTHROID PROGENITOR CELLS Trailhead Biosystems Inc. (US) 2024-10-16 — — EP claimed
CN-118382694-A Methods and compositions for generating human erythroid progenitors 特雷尔赫德生物系统股份有限公司 2024-07-23 — — CN claimed
WO-2024063818-A9 METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS TRAILHEAD BIOSYSTEMS INC. (US) 2024-05-23 — — WO claimed
WO-2024076758-A1 COMPOSITIONS AND METHODS FOR SMALL MOLECULE BASED EXPANSION OF PLURIPOTENT STEM CELLS TRAILHEAD BIOSYSTEMS INC. (US) 2024-04-11 — — WO claimed
US-20240117302-A1 COMPOSITIONS AND METHODS FOR SMALL MOLECULE BASED EXPANSION OF PLURIPOTENT STEM CELLS TRAILHEAD BIOSYSTEMS INC. 2024-04-11 — — US claimed
WO-2024063818-A2 METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS TRAILHEAD BIOSYSTEMS INC. (US) 2024-03-28 — — WO claimed
US-20240043798-A1 METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS TRAILHEAD BIOSYSTEMS INC. 2024-02-08 — — US claimed
US-11596657-B2 Use of AhR agonist for the preventive or curative treatment of metabolic syndrome and the associated disorders INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) 2023-03-07 — — US claimed
CN-112716934-A Application of 7-methoxyisoflavone in endothelial inflammation 华中科技大学同济医学院附属协和医院 2021-04-30 — — CN claimed
CN-109674781-B Application of 7-methoxyisoflavone in preparing medicine for treating allergic diseases and autoimmune diseases 中国药科大学 2021-03-12 — — CN claimed
US-20190282638-A1 USE OF AHR AGONIST FOR THE PREVENTIVE OR CURATIVE TREATMENT OF METABOLIC SYNDROME AND THE ASSOCIATED DISORDERS INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (FR) 2019-09-19 — — US claimed
EP-3522902-A1 USE OF AHR AGONIST FOR THE PREVENTIVE OR CURATIVE TREATMENT OF METABOLIC SYNDROME AND THE ASSOCIATED DISORDERS Institut National de la Recherche Agronomique (FR) 2019-08-14 — — EP claimed
CN-109674781-A Application of 7-methoxyisoflavone in preparing medicine for treating allergic diseases and autoimmune diseases 中国药科大学 2019-04-26 — — CN claimed
WO-2018065132-A1 USE OF AHR AGONIST FOR THE PREVENTIVE OR CURATIVE TREATMENT OF METABOLIC SYNDROME AND THE ASSOCIATED DISORDERS. INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) 2018-04-12 — — WO claimed
CN-101591324-B Three crystal forms of 5-methyl-7-methoxyisoflavone, preparation method thereof, pharmaceutical composition thereof and application thereof INST MATERIA MEDICA CAMS 2013-07-10 — — CN claimed
CN-101591324-A Three crystal forms of 5-methyl-7-methoxyisoflavone, preparation method thereof, pharmaceutical composition thereof and application thereof INST MATERIA MEDICA CAMS (CN) 2009-12-02 — — CN claimed
US-20090253782-A1 Compounds for Enhancing Arginase Activity and Methods of USe Thereof CORNELL RESEARCH FOUNDATION, INC. 2009-10-08 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090253782-A1 Compounds for Enhancing Arginase Activity and Methods of USe Thereof ARG2, ARG1, OTC MAPT 3726/4885ALDH1A1 292/4885SMN1; SMN2 90/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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