Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505504 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2RECQLACHEHRH3TSHR | |
| SCHEMBL5500621 | 0.93 | HRH3 (0.48) | SMN1; SMN2RECQLACHEHRH3TSHR | |
| SCHEMBL5500648 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2RECQLACHETSHRDRD2 | |
| SCHEMBL5504700 | 0.77 | ACHE (0.46) | ACHEHRH3DRD2DRD4DRD3 | |
| SCHEMBL5505503 | 0.77 | ACHE (0.46) | ACHEHRH3DRD2DRD4DRD3 | |
| SCHEMBL3709310 | 0.76 | RECQL (0.70) | SMN1; SMN2RECQLACHETSHRDRD2 | |
| SCHEMBL7474059 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2RECQLACHETSHRDRD2 | |
| SCHEMBL5505366 | 0.75 | HRH3 (0.36) | HRH3 | |
| SCHEMBL5505363 | 0.75 | HRH3 (0.36) | HRH3 | |
| Hydrochloric Acid SCHEMBL3706762 | 0.75 | RECQL (0.68) | SMN1; SMN2RECQLACHETSHRDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |