Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505504 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2RECQLTSHRDRD2DRD4 | |
| SCHEMBL5504701 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2RECQLTSHRDRD2DRD4 | |
| SCHEMBL5500621 | 0.77 | HRH3 (0.48) | SMN1; SMN2RECQLTSHRDRD2DRD4 | |
| SCHEMBL5500642 | 0.77 | DRD2 (0.43) | SMN1; SMN2RECQLDRD2DRD4DRD3 | |
| SCHEMBL3393340 | 0.77 | MC4R (0.56) | DRD2DRD4DRD3ACHEMC4R | |
| SCHEMBL8176219 | 0.77 | MC4R (0.56) | DRD2DRD4DRD3ACHEMC4R | |
| SCHEMBL3393342 | 0.77 | MC4R (0.56) | DRD2DRD4DRD3ACHEMC4R | |
| SCHEMBL3709310 | 0.76 | RECQL (0.70) | SMN1; SMN2RECQLTSHRDRD2DRD4 | |
| SCHEMBL5505487 | 0.75 | CYP1A2 (0.45) | ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL3706762 | 0.75 | RECQL (0.68) | SMN1; SMN2RECQLTSHRDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |