Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27689729 | 1.00 | REN (0.70) | RENCYP3A4 | |
| SCHEMBL5603647 | 0.91 | REN (0.69) | RENCYP3A4 | |
| SCHEMBL5509846 | 0.91 | REN (0.69) | RENCYP3A4 | |
| SCHEMBL27758544 | 0.89 | REN (0.69) | RENCYP3A4 | |
| SCHEMBL4789098 | 0.89 | REN (0.69) | RENCYP3A4 | |
| SCHEMBL1863420 | 0.89 | REN (0.68) | REN | |
| SCHEMBL1863419 | 0.89 | REN (0.68) | REN | |
| SCHEMBL4752903 | 0.84 | REN (0.53) | REN | |
| SCHEMBL5510417 | 0.84 | REN (0.53) | REN | |
| SCHEMBL5503909 | 0.84 | REN (0.68) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101072561-B | Diaminoalkane aspartic protease inhibitors | VITAE PHARMACEUTICALS INC | 2011-05-11 | — | — | CN | disclosed |
| CN-101072561-A | Diaminoalkane aspartic protease inhibitors | VITAE PHARMACEUTICALS INC (US) | 2007-11-14 | — | — | CN | disclosed |
| EP-1807078-A1 | DIAMINOALKANE ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006042150-A1 | DIAMINOALKANE ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2006-04-20 | — | — | WO | disclosed |