Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5513344 | 0.90 | PTGDR2 (0.56) | PTGDR2LMNAMEN1KMT2APOLB | |
| SCHEMBL5497575 | 0.85 | PTGDR2 (0.74) | PTGDR2LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL5507284 | 0.79 | KMT2A (0.43) | PTGDR2LMNAKMT2AMAPT | |
| SCHEMBL6977049 | 0.78 | LMNA (0.76) | PTGDR2LMNANPSR1P2RY1 | |
| SCHEMBL5444441 | 0.78 | PTGDR2 (0.52) | PTGDR2LMNAMEN1KMT2AMAPT | |
| SCHEMBL6972357 | 0.76 | LMNA (0.72) | PTGDR2LMNANPSR1 | |
| SCHEMBL6972361 | 0.76 | LMNA (0.72) | PTGDR2LMNANPSR1 | |
| SCHEMBL6972352 | 0.76 | LMNA (0.72) | PTGDR2LMNANPSR1 | |
| SCHEMBL4128372 | 0.75 | PTGDR2 (0.86) | PTGDR2LMNAMEN1KMT2APOLB | |
| SCHEMBL4516714 | 0.75 | PTGDR2 (0.86) | PTGDR2LMNAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740547-A1 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005100321-A1 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-10-27 | — | — | WO | disclosed |