Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3868884 | 0.83 | MEN1 (0.47) | MAPTALDH1A1GAAHTTCNR2 | |
| SCHEMBL6555114 | 0.80 | ALDH1A1 (0.39) | MAPTALDH1A1GAAKDM4EMAPK1 | |
| SCHEMBL9197023 | 0.78 | S100B (0.66) | MAPTALDH1A1GAAMAPK1HTT | |
| SCHEMBL15741279 | 0.77 | ALDH1A1 (0.54) | MAPTALDH1A1GAAKDM4EMAPK1 | |
| SCHEMBL6984098 | 0.75 | ALDH1A1 (0.66) | MAPTALDH1A1GAAKDM4EMAPK1 | |
| SCHEMBL12227010 | 0.75 | PARP1 (0.44) | ALDH1A1GAAKDM4ETHRBGFER | |
| SCHEMBL6443035 | 0.74 | ALDH1A1 (0.51) | MAPTALDH1A1GAAKDM4EMAPK1 | |
| SCHEMBL9463877 | 0.74 | MAPT (0.51) | MAPTALDH1A1GAAKDM4EMAPK1 | |
| SCHEMBL22504113 | 0.72 | AOC3 (0.58) | MAPTALDH1A1GAAKDM4EMAPK1 | |
| SCHEMBL11222351 | 0.71 | ALDH1A1 (0.60) | MAPTALDH1A1GAAKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799645-A2 | PROCESSES AND INTERMEDIATES FOR PREPARING CYSTEINE PROTEASE INHIBITORS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006034004-A2 | PROCESSES AND INTERMEDIATES FOR PREPARING CYSTEINE PROTEASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2006-03-30 | — | — | WO | disclosed |