SCHEMBL5504965

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8266580	0.86	NPC1 (0.38)	NPC1ALDH1A1POLBRAB9AMEN1
	SCHEMBL5503763	0.80	CHRNA7 (0.44)	NPC1ALDH1A1POLBRAB9AMAPT
	SCHEMBL5510096	0.79	CYP2D6 (0.49)	ALDH1A1RAB9AMEN1KMT2AMAPT
	Hydrochloric Acid SCHEMBL5508193	0.79	CHRNA7 (0.43)	NPC1ALDH1A1POLBRAB9AMAPT
	SCHEMBL5509094	0.79	RAB9A (0.42)	NPC1ALDH1A1POLBRAB9AMEN1
	SCHEMBL5505983	0.77	MAPT (0.58)	NPC1ALDH1A1POLBRAB9AMEN1
	SCHEMBL5507406	0.75	MAPT (0.51)	ALDH1A1POLBMEN1KMT2ASMN1; SMN2
	SCHEMBL5511181	0.74	NPC1 (0.44)	NPC1ALDH1A1POLBRAB9AKMT2A
	SCHEMBL5508873	0.73	NPC1 (0.43)	NPC1ALDH1A1POLBRAB9AKMT2A
	SCHEMBL5508874	0.72	SLC16A3 (0.52)	NPC1ALDH1A1POLBRAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.