Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.49 |
| ▸ | ACE | P12821 | 7/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 7/20 | 0.49 |
| ▸ | CPA1 | P15085 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.47 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1109641 | 0.91 | CPA3 (0.50) | MMEGAA | |
| SCHEMBL1031027 | 0.91 | CPA3 (0.50) | MMEGAA | |
| SCHEMBL515921 | 0.91 | CPA3 (0.50) | MMEGAA | |
| Hydrochloric Acid SCHEMBL28182328 | 0.90 | CPA3 (0.49) | MMEGAA | |
| Hydrochloric Acid SCHEMBL1927540 | 0.90 | CPA3 (0.49) | MMEGAA | |
| Hydrochloric Acid SCHEMBL1927541 | 0.90 | CPA3 (0.49) | MMEGAA | |
| Benzenemethanethiol SCHEMBL11584239 | 0.87 | IDO1 (0.47) | MMEGAA | |
| SCHEMBL7614779 | 0.83 | ACE (0.49) | ACELMNAFFAR1 | |
| SCHEMBL2328314 | 0.83 | ACE (0.49) | ACELMNAFFAR1 | |
| SCHEMBL1760830 | 0.83 | ALDH1A1 (0.50) | MMEACELMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833978-A1 | TRIPEPTIDE AND TETRAPEPTIDE THIOETHERS | TELIK, INC. (US) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006074249-A1 | TRIPEPTIDE AND TETRAPEPTIDE THIOETHERS | TELIK, INC. (US) | 2006-07-13 | — | — | WO | disclosed |