Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GALK1 | P51570 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5951222 | 0.83 | IDO1 (0.48) | IDO1MTNR1AMAPTMAPK1ALDH1A1 | |
| SCHEMBL5505283 | 0.81 | CYP19A1 (0.40) | MAPTALDH1A1HPGDKDM4EHTR1A | |
| SCHEMBL5951252 | 0.79 | ACHE (0.56) | MAPTALDH1A1HPGDNPSR1KDM4E | |
| SCHEMBL5952027 | 0.76 | HTR7 (0.39) | MAPTALDH1A1HPGDNPSR1KDM4E | |
| SCHEMBL5953322 | 0.76 | HTR7 (0.43) | MAPTALDH1A1HPGDHTR1AHTR7 | |
| SCHEMBL5952199 | 0.76 | HTR7 (0.41) | MAPTALDH1A1HPGDNPSR1KDM4E | |
| SCHEMBL5951730 | 0.75 | ACHE (0.45) | MAPTMAPK1ALDH1A1HPGDNPSR1 | |
| SCHEMBL10685434 | 0.74 | IDO1 (0.53) | IDO1MTNR1AMAPTMAPK1ALDH1A1 | |
| SCHEMBL5953305 | 0.74 | HTR7 (0.44) | MTNR1AMAPTALDH1A1HPGDHTR1A | |
| SCHEMBL15874769 | 0.74 | CYP19A1 (0.52) | IDO1MTNR1AMAPTMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007326874-A | METHOD FOR PRODUCING SUBSTITUTED INDANONE | TARGOR GMBH | 2007-12-20 | — | — | JP | disclosed |