Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA6 | P23280 | 5/20 | 0.46 |
| ▸ | CA7 | P43166 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA4 | P22748 | 4/20 | 0.46 |
| ▸ | CA5A | P35218 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CA3 | P07451 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701839 | 1.00 | CA12 (0.46) | CA12CA6CA7CA9CA14 | |
| SCHEMBL978206 | 0.98 | CA12 (0.46) | CA12CA6CA7CA9CA14 | |
| SCHEMBL34460494 | 0.92 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL9702836 | 0.91 | CYP2C19 (0.32) | ALDH1A1CASP2MEN1KMT2ACYP1A2 | |
| SCHEMBL558057 | 0.89 | CYP2C19 (0.33) | ALDH1A1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL17937723 | 0.88 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL14732727 | 0.87 | CA12 (0.46) | CA12CA6CA7CA9CA14 | |
| SCHEMBL12191368 | 0.85 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL12191358 | 0.85 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL3834546 | 0.84 | CA12 (0.34) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160919-A1 | Reactive filler for dental cements | DENTSPLY DE TREY GMBH (DE) | 2006-07-20 | — | — | US | claimed |
| WO-1992005433-A1 | CONTINUOUS POSITIVE CHARGE CAPILLARY COLUMNS USED IN CAPILLARY ELECTROPHORESIS | KERR ROBERT (FR) | 1992-04-02 | — | — | WO | claimed |
| EP-4722222-A1 | BISSILYL COMPOUND HAVING SILYL GROUP SUBSTITUTED WITH ORGANOXYSILYLALKYLAMINO GROUP AND METHOD FOR PRODUCING SAME, AND COMPOSITION AND CURED PRODUCT CONTAINING SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2026-04-08 | — | — | EP | disclosed |
| EP-3984516-A1 | COMPOSITE FILLER PARTICLES AND PROCESS FOR THE PREPARATION THEREOF | Dentsply DeTrey GmbH (DE) | 2022-04-20 | — | — | EP | disclosed |
| US-10040969-B2 | Composite filler particles and process for the preparation thereof | DENTSPLY SIRONA INC. (US) | 2018-08-07 | — | — | US | disclosed |
| US-20160024334-A1 | COMPOSITE FILLER PARTICLES AND PROCESS FOR THE PREPARATION THEREOF | DENTSPLY INTERNATIONAL INC. (US) | 2016-01-28 | — | — | US | disclosed |
| US-9193849-B2 | Composite filler particles and process for the preparation thereof | DENTSPLY INTERNATIONAL INC. (US) | 2015-11-24 | — | — | US | disclosed |
| US-20130158157-A1 | COMPOSITE FILLER PARTICLES AND PROCESS FOR THE PREPARATION THEREOF | DENTSPLY INTERNATIONAL INC. (US) | 2013-06-20 | — | — | US | disclosed |
| EP-1789008-A1 | REACTIVE FILLER FOR DENTAL CEMENTS | DENTSPLY DETREY GmbH (DE) | 2007-05-30 | — | — | EP | disclosed |
| US-20060160919-A1 | Reactive filler for dental cements | DENTSPLY DE TREY GMBH (DE) | 2006-07-20 | — | — | US | disclosed |
| WO-2006013111-A1 | REACTIVE FILLER FOR DENTAL CEMENTS | DENTSPLY DETREY GMBH (DE) | 2006-02-09 | — | — | WO | disclosed |
| WO-1992005433-A1 | CONTINUOUS POSITIVE CHARGE CAPILLARY COLUMNS USED IN CAPILLARY ELECTROPHORESIS | KERR ROBERT (FR) | 1992-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10040969-B2 | Composite filler particles and process for the preparation thereof | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, C9, H1-10 | CA12 3771/4885CA6 4210/4885CA7 3659/4885 |
| US-20060160919-A1 | Reactive filler for dental cements | CD44, L1CAM, ITGAM | CA12 1706/4885CA6 2196/4885CA7 2615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.