Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.42 |
| ▸ | DRD3 | P35462 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2784305 | 0.87 | MAPT (0.39) | ADRA1DADRA1AADRA1BMEN1TSHR | |
| SCHEMBL2783449 | 0.87 | MAPT (0.37) | DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL2784296 | 0.86 | DRD2 (0.56) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL2783851 | 0.86 | DRD2 (0.56) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL5522338 | 0.80 | DRD2 (0.37) | DRD2DRD3HTR1A | |
| SCHEMBL2781685 | 0.77 | DRD2 (0.42) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL2782566 | 0.77 | MEN1 (0.44) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL2783740 | 0.76 | HTR6 (0.43) | ADRA1DADRA1AADRA1BTSHR | |
| SCHEMBL3105655 | 0.76 | DRD4 (0.41) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL2782561 | 0.75 | DRD2 (0.44) | DRD2DRD3HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773772-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES/PIPERAZINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2007-04-18 | — | — | EP | claimed |
| WO-2005121087-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES/PIPERAZINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2005-12-22 | — | — | WO | claimed |