Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.58 |
| ▸ | MAOB | P27338 | 5/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | PRKX | P51817 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1563170 | 0.91 | S1PR1 (0.48) | S1PR1MAOBMAOABCHEPRKX | |
| SCHEMBL1563615 | 0.89 | S1PR1 (0.55) | S1PR1MAOBMAOACCNB2CDK1 | |
| SCHEMBL5505756 | 0.85 | S1PR1 (0.63) | S1PR1MAOBBCHECYP4F2CYP4A11 | |
| SCHEMBL1563997 | 0.85 | S1PR1 (0.58) | S1PR1MAOBMAOABCHECYP4F2 | |
| SCHEMBL16355892 | 0.84 | S1PR1 (0.52) | S1PR1MAOBMAOACCNB2CDK1 | |
| SCHEMBL13265616 | 0.84 | S1PR1 (0.60) | S1PR1MAOBMAOACCNB2CDK1 | |
| SCHEMBL13285272 | 0.84 | S1PR1 (0.60) | S1PR1MAOBMAOACCNB2CDK1 | |
| SCHEMBL1563640 | 0.83 | S1PR1 (0.56) | S1PR1MAOBMAOABCHECYP4F2 | |
| SCHEMBL1564052 | 0.83 | S1PR1 (0.61) | S1PR1MAOBBCHECYP4F2CYP4A11 | |
| SCHEMBL13265617 | 0.83 | S1PR1 (0.56) | S1PR1MAOBMAOACCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1431284-B1 | DIARYL SULFIDE DERIVATIVE, ADDITION SALT THEREOF, AND IMMUNOSUPPRESSANT | KYORIN SEIYAKU KK (JP) | 2007-11-21 | — | — | EP | disclosed |
| US-6960692-B2 | 2-amino-2-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]propyl-1,3-propanediol; autoimmune diseases, rheumatoid arthritis, psoriasis, dermatitis, asthma, hay fever, anti-rejection of organ or bone marrow transplants; side effect reduction | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20040254222-A1 | Diaryl sulfide derivative, addition salt thereof, and immunosuppressant | PRIOTHERA LIMITED (IE) | 2004-12-16 | — | — | US | disclosed |
| EP-1431284-A1 | DIARYL SULFIDE DERIVATIVE, ADDITION SALT THEREOF, AND IMMUNOSUPPRESSANT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2004-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254222-A1 | Diaryl sulfide derivative, addition salt thereof, and immunosuppressant | TST, IL2, CBS | S1PR1 993/4885MAOB 4319/4885MAOA 4639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.