Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 18/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.54 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505648 | 1.00 | ADORA1 (0.54) | ADORA1ADORA3ADORA2BADORA2ASLC28A1 | |
| SCHEMBL5503445 | 0.95 | ADORA1 (0.49) | ADORA1ADORA3ADORA2BADORA2ASLC28A1 | |
| SCHEMBL5503453 | 0.95 | ADORA1 (0.49) | ADORA1ADORA3ADORA2BADORA2ASLC28A1 | |
| SCHEMBL5504164 | 0.89 | TSHR (0.52) | ADORA1ADORA3ADORA2BADORA2ASLC29A1 | |
| SCHEMBL5504161 | 0.89 | TSHR (0.52) | ADORA1ADORA3ADORA2BADORA2ASLC29A1 | |
| SCHEMBL5509613 | 0.89 | ADORA3 (0.49) | ADORA1ADORA3ADORA2BADORA2ASLC29A1 | |
| SCHEMBL5509065 | 0.89 | TSHR (0.52) | ADORA1ADORA3ADORA2BADORA2ASLC29A1 | |
| SCHEMBL5509240 | 0.89 | TSHR (0.52) | ADORA1ADORA3ADORA2BADORA2ASLC29A1 | |
| SCHEMBL5513305 | 0.88 | ADORA2A (0.52) | ADORA1ADORA3ADORA2BADORA2ASLC29A1 | |
| SCHEMBL5513298 | 0.88 | ADORA2A (0.52) | ADORA1ADORA3ADORA2BADORA2ASLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537133-B1 | PARTIAL AND FULL AGONISTS OF A1 ADENOSINE RECEPTORS | CV THERAPEUTICS INC (US) | 2007-07-25 | — | — | EP | disclosed |