Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 3/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5504838 | 0.85 | SIGMAR1 (0.41) | HRH3CHRM2CHRM1 | |
| SCHEMBL5505700 | 0.84 | HRH3 (0.38) | HRH3PDCD1CD274USP2TSHR | |
| SCHEMBL5501796 | 0.83 | ALDH1A1 (0.35) | HRH3USP2TSHRALDH1A1POLB | |
| SCHEMBL5508184 | 0.82 | HRH3 (0.41) | HRH3HRH2HRH1CHRM2CHRM1 | |
| SCHEMBL5504002 | 0.80 | HRH3 (0.39) | HRH3USP2TSHRALDH1A1POLB | |
| SCHEMBL5504695 | 0.80 | HRH3 (0.40) | HRH3PDCD1CD274CHRM2CHRM1 | |
| SCHEMBL5502185 | 0.79 | HRH3 (0.41) | HRH3USP2TSHRALDH1A1POLB | |
| SCHEMBL5505456 | 0.79 | CSNK2A2 (0.33) | HRH3USP2TSHRALDH1A1POLB | |
| SCHEMBL5502428 | 0.78 | HRH3 (0.37) | HRH3USP2TSHRALDH1A1POLB | |
| SCHEMBL5508093 | 0.77 | USP2 (0.34) | HRH3USP2TSHRHRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |