SCHEMBL5506124

SCHEMBL5506124

N#CCCCNc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.64
MAPT P10636 1/20 0.64
GAA P10253 3/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
HTT P42858 1/20 0.42
THRB P10828 1/20 0.41
ICMT O60725 1/20 0.39
USP2 O75604 1/20 0.39
HSD17B10 Q99714 1/20 0.39
POLB P06746 1/20 0.37
CNR2 P34972 1/20 0.37
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
NCOR2 Q9Y618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4550523 0.94 ALDH1A1 (0.61) ALDH1A1MAPTGAAL3MBTL1HTT
SCHEMBL10499283 0.92 ALDH1A1 (0.59) ALDH1A1MAPTGAAL3MBTL1HTT
SCHEMBL141474 0.87 GAA (0.58) ALDH1A1MAPTGAAL3MBTL1HTT
SCHEMBL11253095 0.84 MAPT (0.46) ALDH1A1MAPTHTTTHRBPOLB
SCHEMBL11258268 0.83 ALDH1A1 (0.48) ALDH1A1MAPTGAAHTT
SCHEMBL5504318 0.83 GAA (0.46) ALDH1A1MAPTGAAHTTTHRB
SCHEMBL7100388 0.80 GAA (0.47) ALDH1A1MAPTGAAL3MBTL1HTT
SCHEMBL11309666 0.80 ALDH1A1 (0.48) ALDH1A1MAPTGAAL3MBTL1HTT
SCHEMBL5551251 0.80 MAPT (0.59) ALDH1A1MAPTGAAL3MBTL1HTT
SCHEMBL11650662 0.80 ALDH1A1 (0.56) ALDH1A1MAPTGAAL3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119875390-A 3- [ [4- [ (2-R3) R4 amino-3-R2 ] phenyl ] azo ] -R1-nitrobenzene red dye and preparation method thereof 浙江大恒新材料有限公司 2025-04-25 CN claimed
US-20260108521-A1 GSPT1 DEGRADERS, COMPOSITIONS COMPRISING THE DEGRADER, AND METHODS OF USING THE SAME BIOFRONT LTD (KY) 2026-04-23 US disclosed
EP-4598918-A1 GSPT1 DEGRADERS, COMPOSITIONS COMPRISING THE DEGRADER, AND METHODS OF USING THE SAME BIOFRONT LTD (KY) 2025-08-13 EP disclosed
CN-119875390-A 3- [ [4- [ (2-R3) R4 amino-3-R2 ] phenyl ] azo ] -R1-nitrobenzene red dye and preparation method thereof 浙江大恒新材料有限公司 2025-04-25 CN disclosed
WO-2024073871-A1 GSPT1 DEGRADERS, COMPOSITIONS COMPRISING THE DEGRADER, AND METHODS OF USING THE SAME BIOFRONT LTD (KY) 2024-04-11 WO disclosed
CN-102361887-A Polymers functionalized with nitrile compounds containing a protected amino group BRIDGESTONE CORP 2012-02-22 CN disclosed
EP-1846383-A2 RIGIDIFIED COMPOUNDS FOR MODULATING HEPARANASE ACTIVITY Insight Biopharmaceuticals Ltd. (IL) 2007-10-24 EP disclosed
WO-2006072953-A2 RIGIDIFIED COMPOUNDS FOR MODULATING HEPARANASE ACTIVITY INSIGHT BIOPHARMACEUTICALS LTD. (IL) 2006-07-13 WO disclosed
EP-1259475-A4 TRANSITION METAL-CATALYZED PROCESS FOR ADDITION OF AMINES TO CARBON-CARBON DOUBLE BONDS UNIV YALE (US) 2004-08-18 EP disclosed
EP-1259475-A1 TRANSITION METAL-CATALYZED PROCESS FOR ADDITION OF AMINES TO CARBON-CARBON DOUBLE BONDS YALE UNIVERSITY (US) 2002-11-27 EP disclosed
US-6479592-B2 SUITABLE IN AS A DENTAL MATERIAL AND ESPECIALLY AS A CONSTITUENT OF DENTAL ADHESIVES OWING TO AN ADHESION-BOOSTING EFFECT IVOCLAR VIVADENT AG (DE) 2002-11-12 US disclosed
WO-2001064620-A1 TRANSITION METAL-CATALYZED PROCESS FOR ADDITION OF AMINES TO CARBON-CARBON DOUBLE BONDS YALE UNIVERSITY (US) 2001-09-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108521-A1 GSPT1 DEGRADERS, COMPOSITIONS COMPRISING THE DEGRADER, AND METHODS OF USING THE SAME GHSR, GSPT1, GLRA1 ALDH1A1 3997/4885MAPT 910/4885GAA 1275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.