Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL709983 | 0.99 | SLC6A9 (0.45) | SLC6A9SLC6A4CARM1PRMT6MAPK14 | |
| SCHEMBL3770904 | 0.88 | CARM1 (0.44) | SLC6A9SLC6A4CARM1PRMT6MAPK14 | |
| SCHEMBL3775184 | 0.83 | CARM1 (0.54) | SLC6A9CARM1PRMT6MAPK14CHRM3 | |
| SCHEMBL708522 | 0.82 | CARM1 (0.50) | SLC6A9CARM1PRMT6MAPK14CHRM3 | |
| SCHEMBL5515777 | 0.82 | CARM1 (0.53) | SLC6A9CARM1PRMT6MAPK14CETP | |
| SCHEMBL5506745 | 0.81 | CARM1 (0.52) | SLC6A9CARM1PRMT6MAPK14CHRM3 | |
| SCHEMBL5513104 | 0.81 | DPP7 (0.47) | SLC6A4CARM1PRMT6HTR2C | |
| SCHEMBL3783236 | 0.81 | ATM (0.37) | CETPHTR2C | |
| Hydrochloric Acid SCHEMBL710200 | 0.80 | CARM1 (0.51) | SLC6A9CARM1PRMT6MAPK14CHRM3 | |
| SCHEMBL5509533 | 0.80 | CARM1 (0.48) | SLC6A9CARM1PRMT6MAPK14CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869019-B1 | BICYCLIC [3.1.0] HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PROD INC (US) | 2014-08-27 | — | — | EP | claimed |
| EP-1869019-A1 | BICYCLIC [3.1.0] HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | Pfizer Products Incorporated (US) | 2007-12-26 | — | — | EP | claimed |
| WO-2006106425-A1 | BICYCLIC [3.1.0] HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PRODUCTS INC. (US) | 2006-10-12 | — | — | WO | claimed |
| EP-1869019-B1 | BICYCLIC [3.1.0] HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PROD INC (US) | 2014-08-27 | — | — | EP | disclosed |