SCHEMBL5506672

SCHEMBL5506672

O=C(O)CCCCC(=O)OC(=O)C(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 4/20 0.44
CHRM3 P20309 4/20 0.44
CHRM2 P08172 3/20 0.44
CHRM4 P08173 3/20 0.44
HDAC3 O15379 2/20 0.43
HDAC4 P56524 2/20 0.43
HDAC1 Q13547 2/20 0.43
HDAC7 Q8WUI4 2/20 0.43
HDAC2 Q92769 2/20 0.43
HDAC10 Q969S8 2/20 0.43
HDAC11 Q96DB2 2/20 0.43
HDAC8 Q9BY41 2/20 0.43
HDAC6 Q9UBN7 2/20 0.43
HDAC9 Q9UKV0 2/20 0.43
HDAC5 Q9UQL6 2/20 0.43
MAPT P10636 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
CYP2D6 P10635 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
CYP3A4 P08684 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4645604 0.85 CHRM1 (0.43) CHRM1CHRM3CHRM2CHRM4HDAC3
SCHEMBL4642470 0.81 CHRM1 (0.45) CHRM1CHRM3CHRM2CHRM4HDAC3
Diphenylacetic Acid SCHEMBL5506668 0.78 HDAC3 (0.52) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL329046 0.78 L3MBTL1 (0.60) CHRM1CHRM3CHRM2CHRM4HDAC3
SCHEMBL4645901 0.77 CHRM1 (0.47) CHRM1CHRM3CHRM2CHRM4HDAC3
SCHEMBL28833591 0.76 CRHBP (0.49) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL4644117 0.75 CHRM1 (0.41) CHRM1CHRM3CHRM2CHRM4MAPT
SCHEMBL27716236 0.75 HDAC3 (0.49) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL27702248 0.75 CRHBP (0.48) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL27333858 0.75 HDAC3 (0.49) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7166653-B2 Transparent polymer articles of low thickness CIBA SPECIALTY CHEMICALS CORP. (US) 2007-01-23 US disclosed
US-20030236327-A1 Agriculture thin film; hydroxyphenyl triazine ultraviolet radiation absorber; screening solar radiation LEPPARD DAVID GEORGE (CH) 2003-12-25 US disclosed
EP-0473542-B1 Thioaminal stabilizers CIBA GEIGY AG (CH) 1994-05-11 EP disclosed
EP-0473542-A1 Thioaminal stabilizers CIBA-GEIGY AG (CH) 1992-03-04 EP disclosed