Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4570191 | 1.00 | HSD11B1 (0.38) | HSD11B1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2698001 | 1.00 | HSD11B1 (0.38) | HSD11B1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL550673 | 1.00 | HSD11B1 (0.38) | HSD11B1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL550174 | 1.00 | HSD11B1 (0.38) | HSD11B1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2697999 | 1.00 | HSD11B1 (0.38) | HSD11B1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL550175 | 1.00 | HSD11B1 (0.38) | HSD11B1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL550162 | 0.88 | SLC6A9 (0.38) | HSD11B1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL550161 | 0.88 | SLC6A9 (0.38) | HSD11B1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL550338 | 0.83 | HSD11B1 (0.43) | HSD11B1KDM4EFASNALK | |
| SCHEMBL550337 | 0.83 | HSD11B1 (0.43) | HSD11B1KDM4EFASNALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110581-B2 | Lactam compounds and their use as pharmaceuticals | INCYTE CORPORATION (US) | 2012-02-07 | — | — | US | claimed |