Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | BPTF | Q12830 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960524 | 0.76 | BPTF (0.70) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL4215010 | 0.76 | ALDH1A1 (0.65) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL4521225 | 0.73 | MEN1 (0.65) | MEN1KMT2AGRM1MAPK10L3MBTL1 | |
| SCHEMBL3349162 | 0.72 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL3349176 | 0.72 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL2961251 | 0.70 | MEN1 (0.54) | MEN1KMT2AMAPTALDH1A1GRM1 | |
| SCHEMBL5118148 | 0.70 | MAPT (0.42) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL3357365 | 0.70 | TGFBR1 (0.55) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL3357379 | 0.70 | TGFBR1 (0.55) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL5118141 | 0.69 | MEN1 (0.51) | MEN1KMT2AMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753512-A2 | TETRAHYDROPYRIDOTHIOPHENES | Altana Pharma AG (DE) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005118071-A2 | TETRAHYDROPYRIDOTHIOPHENES | ALTANA PHARMA AG (DE) | 2005-12-15 | — | — | WO | disclosed |