⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL116 | 0.97 | — | — | |
| SCHEMBL25231508 | 0.97 | ALDH1A1 (0.46) | — | |
| SCHEMBL2269356 | 0.94 | — | — | |
| SCHEMBL2269935 | 0.94 | — | — | |
| SCHEMBL10343352 | 0.94 | — | — | |
| SCHEMBL2269360 | 0.94 | — | — | |
| Hydrogen Sulfide SCHEMBL15821640 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL9403872 | 0.94 | — | — | |
| SCHEMBL2271924 | 0.94 | — | — | |
| SCHEMBL29591498 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841339-B1 | Vinylpyrrolidinon cephalosporin derivatives | BASILEA PHARMACEUTICA AG (CH) | 2007-02-21 | — | — | EP | disclosed |
| CN-1081639-C | Vinylpyrrolidinon cephalosporin derivatives | HOFFMANN LA ROCHE (CH) | 2002-03-27 | — | — | CN | disclosed |
| US-6294668-B1 | ANTIBACTERIAL ACTIVITY AGAINST BETA-LACTAM SENSITIVE AND RESISTANT GRAM-POSITIVE BACTERIA, SUCH AS STAPHYLOCOCCI, PNEUMOCOCCI, AND ENTEROCOCCI; USED IN THERAPY OF INFECTIOUS DISEASES CAUSED BY THOSE BACTERIA | HOFFMAN-LA ROCHE INC. | 2001-09-25 | — | — | US | disclosed |
| EP-0841339-A1 | Vinylpyrrolidinon cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1998-05-13 | — | — | EP | disclosed |
| CN-1181382-A | Vinylpyrrolidinon cephalosporin derivatives | HOFFMANN LA ROCHE (CH) | 1998-05-13 | — | — | CN | disclosed |