SCHEMBL5506933

SCHEMBL5506933

Oc1ccc(F)c2c(O)c(F)ccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
HSD17B10 Q99714 2/20 0.41
APP P05067 1/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
CASP1 P29466 1/20 0.41
SNCA P37840 1/20 0.41
RECQL P46063 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PIM1 P11309 1/20 0.38
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36
IDO1 P14902 1/20 0.36
CA3 P07451 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5511548 0.77 EP300 (0.35) TSHRHSD17B10MAPTHPGDALOX15
SCHEMBL5507421 0.76 CA3 (0.37) TSHRHSD17B10APPMAPTTHRB
SCHEMBL5522395 0.74 HPGD (0.70) TSHRHSD17B10APPMAPTTHRB
SCHEMBL7555113 0.74 MAPT (0.39) TSHRHSD17B10APPMAPTTHRB
SCHEMBL7555229 0.74 MAPT (0.39) TSHRHSD17B10APPMAPTTHRB
SCHEMBL5513985 0.73 ERN1 (0.42) MAPTHSD17B1HSD17B2CA3CA6
SCHEMBL5513895 0.73 PIM1 (0.50) TSHRHSD17B10APPMAPTTHRB
SCHEMBL5512543 0.73 IDO1 (0.41) APPIDO1KDM4E
SCHEMBL6351040 0.71 CA6 (0.43) TSHRHSD17B10HPGDALOX15RECQL
SCHEMBL27769273 0.70 HPRT1 (0.52) TSHRHSD17B10APPMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208559-B2 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2007-04-24 US disclosed
US-20060135712-A1 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2006-06-22 US disclosed