Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089273 | 0.81 | CES2 (0.48) | CES2CES1LMNAMEN1FAAH | |
| SCHEMBL29084742 | 0.81 | CES2 (0.48) | CES2CES1LMNAMEN1FAAH | |
| SCHEMBL583014 | 0.81 | CES2 (0.48) | CES2CES1LMNAMEN1FAAH | |
| SCHEMBL7169801 | 0.79 | CES2 (0.46) | CES2CES1MAPTLMNAMEN1 | |
| SCHEMBL10701934 | 0.79 | CES2 (0.46) | CES2CES1MAPTLMNAMEN1 | |
| SCHEMBL9012622 | 0.79 | CES2 (0.46) | CES2CES1MAPTLMNAMEN1 | |
| SCHEMBL7168781 | 0.79 | CES2 (0.46) | CES2CES1MAPTLMNAMEN1 | |
| SCHEMBL7167550 | 0.79 | CES2 (0.46) | CES2CES1MAPTLMNAMEN1 | |
| SCHEMBL3225539 | 0.77 | CES2 (0.44) | CES2CES1LMNAMEN1FAAH | |
| Heptane SCHEMBL6217 | 0.76 | TSHR (0.61) | LMNAMEN1KMT2AGPR84ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192757-B2 | Subtilase variants | NOVOZYMES A/S (DK) | 2007-03-20 | — | — | US | disclosed |
| EP-1081187-B1 | Rubber composition containing silica or silicate and salt of an amine | BRIDGESTONE CORP (JP) | 2004-02-18 | — | — | EP | disclosed |