SCHEMBL8089273

SCHEMBL8089273

CCCCCCC[C](C(C)C)C(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.48
CES1 P23141 3/20 0.48
LMNA P02545 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
FAAH O00519 1/20 0.46
MAPK1 P28482 1/20 0.46
GPR84 Q9NQS5 7/20 0.46
PPARG P37231 6/20 0.46
PPARD Q03181 6/20 0.46
PPARA Q07869 6/20 0.46
HDAC11 Q96DB2 5/20 0.46
TSHR P16473 4/20 0.46
ALDH1A1 P00352 2/20 0.46
TLR2 O60603 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
FABP4 P15090 2/20 0.46
PTPN1 P18031 2/20 0.46
SLC22A6 Q4U2R8 1/20 0.46
SLC22A8 Q8TCC7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29084742 1.00 CES2 (0.48) CES2CES1LMNAMEN1KMT2A
SCHEMBL583014 1.00 CES2 (0.48) CES2CES1LMNAMEN1KMT2A
SCHEMBL7955527 0.88 CES1 (0.43) CES2CES1LMNAMEN1KMT2A
SCHEMBL7269030 0.82 CES2 (0.39) CES2CES1LMNAMEN1KMT2A
SCHEMBL5506970 0.81 CES2 (0.46) CES2CES1LMNAMEN1KMT2A
SCHEMBL6554190 0.80 FFAR4 (0.39) CES2CES1LMNAMEN1KMT2A
SCHEMBL28180233 0.80 CA2 (0.41) LMNAMAPK1FFAR1FFAR4
SCHEMBL3225539 0.79 CES2 (0.44) CES2CES1LMNAMEN1KMT2A
SCHEMBL10456982 0.78 GPR84 (0.52) CES2CES1MEN1KMT2AFAAH
SCHEMBL18614056 0.78 CES2 (0.48) CES2CES1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101604607-A Coating composition for interconnection part of electrode and comprise its plasma display SAMSUNG SDI CO LTD (KR) 2009-12-16 CN claimed
CN-110139882-A High cis-1, 4 block copolymers of polybutadiene and polyisoprene 株式会社普利司通 2019-08-16 CN disclosed
CN-105163853-B The manufacturing method of cyclic carbonate catalyst for synthesizing 丸善石油化学株式会社 2018-06-12 CN disclosed
CN-107835804-A method for preparing carbazole 陶氏环球技术有限责任公司 2018-03-23 CN disclosed
CN-105121013-B The manufacture method of cyclic carbonate catalyst for synthesizing 丸善石油化学株式会社 2017-10-20 CN disclosed
CN-106999802-A Defoamer 圣诺普科有限公司 2017-08-01 CN disclosed
CN-105163854-A Method for producing catalyst for synthesizing cyclic carbonate NAT INST OF ADVANCED IND SCIEN 2015-12-16 CN disclosed
CN-105163853-A Method for manufacturing catalyst for synthesizing cyclic carbonate MARUZEN PETROCHEM CO LTD 2015-12-16 CN disclosed
CN-105121013-A Method for producing catalyst for cyclic carbonate synthesis MARUZEN PETROCHEM CO LTD 2015-12-02 CN disclosed
CN-101604607-A Coating composition for interconnection part of electrode and comprise its plasma display SAMSUNG SDI CO LTD (KR) 2009-12-16 CN disclosed
CN-1648772-A Photosensitive conducting composition for a plasma display panel SAMSUNG SDI CO LTD (KR) 2005-08-03 CN disclosed
EP-1054896-A1 ANALGESIC PEPTIDES FROM VENOM OF $i(GRAMMOSTOLA SPATULATA) AND USE THEREOF ZENECA LIMITED (GB) 2000-11-29 EP disclosed
US-5968838-A SCREENING FOR COMPOUNDS WHICH MIMIC PEPTIDE BINDING ACTIVITY BY LABELING PEPTIDE, BINDING PEPTIDE TO STRETCH ACTIVATED CHANNELS INCUBATING AND DETECCTING BINDING OF COMPOUNDS ZENECA LIMITED (GB) 1999-10-19 US disclosed
WO-1999042480-A1 ANALGESIC PEPTIDES FROM VENOM OF GRAMMOSTOLA SPATULATA AND USE THEREOF ZENECA LIMITED (GB) 1999-08-26 WO disclosed
US-5877026-A SCREENING FOR NEW ANALGESICS WHICH MIMIC THESE POLYPEPTIDES BY COMPARING ACTIVITY OF TEST COMPOUNDS; FOR PAIN RELIEF DURING CANCER WITH SIDE EFFECT REDUCTION ZENECA LIMITED (GB) 1999-03-02 US disclosed
US-5858737-A INCUBATING MIXTURE OF INDENE AND PSEUDOMONAS PUTIDA TO GIVE DESIRED ISOMER OF INDANDIOL MERCK & CO., INC. (US) 1999-01-12 US disclosed
US-5807821-A TREATING CANCER AND POST-SURGERY PAIN; SIDE EFFECT REDUCTION, NON-HABIT FORMING ZENECA LIMITED (GB) 1998-09-15 US disclosed
US-5776896-A Analgesic peptides from venom of grammostola spatulata and use thereof ZENECA LIMITED (GB) 1998-07-07 US disclosed
US-5756663-A MEDIATES HYPOTONIC CELL SWELLING INDUCED CALCIUM INCREASE IN CELLS ZENECA LIMITED (GB) 1998-05-26 US disclosed
WO-1998006866-A1 CONVERSION OF INDENE TO (1S)-AMINO-(2R)-INDANOL FREE OF ANY STEREOISOMER, BY COMBINATION OF DIOXYGENASE BIOCONVERSION AND CHEMICAL STEPS MERCK & CO., INC. (US) 1998-02-19 WO disclosed