Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.40 |
| ▸ | F10 | P00742 | 10/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5504266 | 0.98 | FAAH (0.41) | FAAHTRPV1F10TACR2CNR1 | |
| SCHEMBL5509110 | 0.93 | F10 (0.38) | FAAHTRPV1F10 | |
| SCHEMBL5505624 | 0.91 | FAAH (0.40) | FAAHTRPV1F10TACR2CNR1 | |
| SCHEMBL5505663 | 0.90 | F10 (0.43) | FAAHTRPV1F10 | |
| SCHEMBL5500198 | 0.89 | FAAH (0.42) | FAAHTRPV1F10CNR1CNR2 | |
| SCHEMBL5512361 | 0.88 | F10 (0.43) | FAAHTRPV1F10CNR1CNR2 | |
| SCHEMBL4456117 | 0.88 | F10 (0.41) | F10 | |
| SCHEMBL5508270 | 0.88 | FAAH (0.42) | FAAHTRPV1F10TACR2CNR1 | |
| SCHEMBL5503931 | 0.88 | FAAH (0.44) | FAAHTRPV1F10TACR2CNR1 | |
| SCHEMBL4471614 | 0.86 | CTSL (0.43) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747217-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005111029-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |