Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 5/20 | 0.72 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699986 | 0.89 | NR4A2 (0.72) | NR4A2F7F3PYGL | |
| SCHEMBL1696922 | 0.84 | NR4A2 (0.51) | NR4A2MAPTCREBBPTUBB1 | |
| SCHEMBL3094622 | 0.84 | NR4A2 (1.00) | NR4A2F7F3AVPR1AMAPT | |
| SCHEMBL7360321 | 0.83 | NR4A2 (0.50) | NR4A2MAPTCREBBPALDH1A1TUBB1 | |
| SCHEMBL30009696 | 0.83 | NR4A2 (0.50) | NR4A2MAPTCREBBPTUBB1 | |
| SCHEMBL6511301 | 0.83 | NR4A2 (0.50) | NR4A2MAPTCREBBPTUBB1 | |
| SCHEMBL31618837 | 0.83 | NR4A2 (0.56) | NR4A2MAPTCREBBPTUBB1 | |
| SCHEMBL4780483 | 0.82 | MAPT (0.63) | NR4A2MAPTALDH1A1TUBB1 | |
| SCHEMBL4556456 | 0.81 | NR4A2 (0.73) | NR4A2F7F3AVPR1AMAPT | |
| SCHEMBL3181314 | 0.81 | NR4A2 (0.64) | NR4A2F7F3AVPR1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844011-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | Aventis Pharmaceuticals Inc. (US) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006081343-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | AVENTIS PHARMACEUTICALS INC. (US) | 2006-08-03 | — | — | WO | disclosed |