Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 9/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4375343 | 0.89 | GABRG2 (0.53) | NR4A2GABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL1696922 | 0.84 | NR4A2 (0.51) | NR4A2CREBBPMAPTTUBB1 | |
| SCHEMBL27987692 | 0.84 | NR4A2 (0.70) | NR4A2CREBBPMAPTTUBB1 | |
| SCHEMBL31618837 | 0.83 | NR4A2 (0.56) | NR4A2GABRA1GABRA3CREBBPMAPT | |
| SCHEMBL5507447 | 0.83 | NR4A2 (0.72) | NR4A2CREBBPMAPTTUBB1 | |
| SCHEMBL7360321 | 0.83 | NR4A2 (0.50) | NR4A2GABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL6511301 | 0.83 | NR4A2 (0.50) | NR4A2CREBBPMAPTTUBB1 | |
| SCHEMBL4780483 | 0.82 | MAPT (0.63) | NR4A2MAPTTUBB1 | |
| SCHEMBL1759575 | 0.81 | NR4A2 (0.48) | NR4A2CREBBPMAPTTUBB1 | |
| SCHEMBL1696867 | 0.81 | TUBB1 (0.50) | NR4A2CREBBPMAPTTUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237813-A1 | COMPOUND HAVING ALK INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | 盛世泰科生物医药技术(苏州)有限公司 | 2022-11-17 | — | — | WO | disclosed |