Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5522403 | 0.85 | HCRTR1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL5510323 | 0.81 | KDM4E (0.35) | — | |
| Hydrochloric Acid SCHEMBL5513910 | 0.80 | TP53 (0.33) | — | |
| Hydrochloric Acid SCHEMBL6255444 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL27463818 | 0.76 | PDCD1 (0.33) | — | |
| SCHEMBL6649301 | 0.74 | PDCD1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL4249925 | 0.73 | PDCD1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL5604826 | 0.73 | BRD4 (0.33) | — | |
| SCHEMBL28313073 | 0.73 | PDCD1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL27477688 | 0.73 | PDCD1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208559-B2 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2007-04-24 | — | — | US | disclosed |
| US-20060135712-A1 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2006-06-22 | — | — | US | disclosed |