Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21878401 | 0.78 | KCNH2 (0.64) | KCNH2 | |
| SCHEMBL21878400 | 0.78 | KCNH2 (0.64) | KCNH2 | |
| SCHEMBL21936113 | 0.78 | KCNH2 (0.64) | KCNH2 | |
| SCHEMBL2330705 | 0.74 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL2330709 | 0.74 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL6269567 | 0.73 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL5506989 | 0.73 | ROCK2 (0.46) | KCNH2 | |
| SCHEMBL2331472 | 0.70 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL6267950 | 0.70 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL6279199 | 0.70 | KCNH2 (0.45) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799676-A2 | NEW BICYCLIC ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006032466-A2 | NEW BICYCLIC ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-03-30 | — | — | WO | disclosed |