Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.37 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177741 | 0.81 | AR (0.51) | POLBGAAARLMNAADRB2 | |
| SCHEMBL5498981 | 0.80 | AR (0.50) | POLBGAAARLMNAADRB2 | |
| SCHEMBL13970688 | 0.80 | EPAS1 (0.49) | EPAS1NR1I2HSD11B1 | |
| SCHEMBL7054403 | 0.80 | GAA (0.64) | POLBGAAARSMN1; SMN2PIN1 | |
| SCHEMBL4173770 | 0.79 | GAA (0.51) | POLBGAAARLMNAADRB2 | |
| SCHEMBL102325 | 0.78 | TSHR (0.48) | GAAARTSHR | |
| SCHEMBL8431375 | 0.78 | GAA (0.62) | POLBGAAARSMN1; SMN2PIN1 | |
| SCHEMBL4438697 | 0.77 | AR (0.50) | ARLMNASMN1; SMN2TSHREPAS1 | |
| SCHEMBL28625665 | 0.77 | AR (0.61) | POLBGAAARSMN1; SMN2PIN1 | |
| Hydrochloric Acid SCHEMBL16792416 | 0.75 | GAA (0.45) | POLBGAAARSMN1; SMN2PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781280-A2 | ANDROGEN MODULATORS | Warner-Lambert Company LLC (US) | 2007-05-09 | — | — | EP | claimed |
| WO-2006018723-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2006-02-23 | — | — | WO | claimed |