Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.44 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5507928 | 0.81 | POLB (0.50) | ARPOLBGAATSHRLMNA | |
| SCHEMBL5498981 | 0.81 | AR (0.50) | ARSLC22A12POLBGAATSHR | |
| SCHEMBL28625665 | 0.78 | AR (0.61) | ARSLC22A12POLBGAATSHR | |
| SCHEMBL5498436 | 0.77 | AR (0.47) | ARSLC22A12POLBGAATSHR | |
| SCHEMBL11440814 | 0.76 | RAB9A (0.48) | ARGAATSHRHTR1ASLC6A2 | |
| SCHEMBL27937397 | 0.76 | TSHR (0.47) | ARSLC22A12POLBGAATSHR | |
| SCHEMBL27937348 | 0.76 | KDM4E (0.42) | ARSLC22A12POLBGAAHTR1A | |
| SCHEMBL4175286 | 0.75 | AR (0.48) | ARSLC22A12POLBGAATSHR | |
| SCHEMBL7054403 | 0.73 | GAA (0.64) | ARSLC22A12POLBGAATSHR | |
| SCHEMBL4173770 | 0.73 | GAA (0.51) | ARSLC22A12POLBGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399137-A4 | SULFONAMIDES | SMITHKLINE BEECHAM CORP (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1387679-A4 | SULFONAMIDES | SMITHKLINE BEECHAM CORP (US) | 2004-08-11 | — | — | EP | disclosed |
| EP-1399137-A1 | SULFONAMIDES | SmithKline Beecham Corporation (US) | 2004-03-24 | — | — | EP | disclosed |
| EP-1387679-A1 | SULFONAMIDES | SmithKline Beecham Corporation (US) | 2004-02-11 | — | — | EP | disclosed |
| WO-2002089793-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-11-14 | — | — | WO | disclosed |
| WO-2002089785-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-11-14 | — | — | WO | disclosed |