Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5508129 | 0.77 | TLR8 (0.40) | TLR8TLR7GAAMAPK1ALDH1A1 | |
| SCHEMBL5504239 | 0.74 | POLB (0.45) | NPC1RAB9AGAAMAPK1SMN1; SMN2 | |
| SCHEMBL5501897 | 0.74 | TLR8 (0.47) | TLR8TLR7NPC1RAB9AMAPK1 | |
| SCHEMBL11865568 | 0.73 | NPC1 (0.43) | TLR8TLR7NPC1RAB9AGAA | |
| SCHEMBL5506839 | 0.73 | HSD17B10 (0.39) | TLR8NPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL5510456 | 0.73 | TP53 (0.36) | TLR8GAAMAPK1ALDH1A1MAPT | |
| SCHEMBL5505676 | 0.73 | SMN1; SMN2 (0.52) | GAAMAPK1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL17856550 | 0.71 | TLR8 (0.45) | TLR8TLR7NPC1RAB9AGAA | |
| SCHEMBL5500718 | 0.69 | CYP3A4 (0.35) | ALDH1A1MAPT | |
| SCHEMBL5504755 | 0.69 | HTT (0.35) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846108-A2 | KERATIN DYEING COMPOSITIONS CONTAINING BENZOTHIAZOLE-4,7-DIAMINES, AND USE THEREOF | The Procter & Gamble Company (US) | 2007-10-24 | — | — | EP | claimed |
| WO-2006078800-A2 | KERATIN DYEING COMPOSITIONS CONTAINING BENZOTHIAZOLE-4-, 7-DIAMINES, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-27 | — | — | WO | claimed |
| US-20060162099-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2006-07-27 | — | — | US | claimed |
| EP-1846108-A2 | KERATIN DYEING COMPOSITIONS CONTAINING BENZOTHIAZOLE-4,7-DIAMINES, AND USE THEREOF | The Procter & Gamble Company (US) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006078800-A2 | KERATIN DYEING COMPOSITIONS CONTAINING BENZOTHIAZOLE-4-, 7-DIAMINES, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-27 | — | — | WO | disclosed |
| US-20060162099-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060162099-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, DSP, KRTCAP2 | TLR8 3044/4885TLR7 2980/4885NPC1 4798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.