SCHEMBL5508192

SCHEMBL5508192

CCN(CC)c1ccc(C2(C=C(c3c(C)n(CC)c4ccc(OC)cc34)c3c(C)n(CC)c4ccc(OC)cc34)OC(=O)c3ccccc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.46
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
POLB P06746 1/20 0.38
ALDH1A1 P00352 3/20 0.37
HSD17B10 Q99714 1/20 0.37
PLA2G2A P14555 2/20 0.37
TSHR P16473 3/20 0.37
MAPT P10636 1/20 0.37
PKM P14618 1/20 0.37
GRIK2 Q13002 1/20 0.36
HTT P42858 1/20 0.35
PTGER4 P35408 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MAOB P27338 1/20 0.34
CNR2 P34972 1/20 0.34
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5510724 0.90 MEN1 (0.33) KDM4EKMT2AMEN1NPC1RAB9A
SCHEMBL7482195 0.89 CNR1 (0.39) KDM4EKMT2AMEN1NPC1RAB9A
SCHEMBL5512734 0.89 ALDH1A1 (0.34) KDM4EKMT2AMEN1NPC1RAB9A
SCHEMBL25608 0.88 ALDH1A1 (0.34) KDM4EKMT2AMEN1RAB9APOLB
SCHEMBL29386399 0.88 ALDH1A1 (0.34) KDM4EKMT2AMEN1RAB9APOLB
SCHEMBL5972724 0.88 MEN1 (0.34) KDM4EKMT2AMEN1NPC1RAB9A
SCHEMBL7479433 0.84 SRD5A1 (0.33) KDM4EKMT2AMEN1RAB9APOLB
SCHEMBL7477171 0.83 CNR2 (0.32) KDM4EKMT2AMEN1RAB9APOLB
SCHEMBL5972836 0.83 TDP1 (0.34) KDM4EKMT2AMEN1POLBALDH1A1
SCHEMBL21415865 0.82 ALDH1A1 (0.34) KMT2AMEN1RAB9AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1631497-A4 LINERLESS LABELS APPLETON PAPER INC (US) 2007-10-17 EP disclosed
US-7125824-B2 Bar codes substrate with two side surface coatings, a thermally-imaging coatings has chromogenic material, 3-[1,1-bis(1,2-dimethylindole-3-yl)ethylene-2-yl]-3-(4-dimethylaminophenyl) -phthalide and Bis(3-Allyl-4-hydroxyphenyl)sulfone developer, the other is pressure sensitive adhesive coatings; nonfading APPLETON PAPERS INC. (US) 2006-10-24 US disclosed
EP-1631497-A2 LINERLESS LABELS Appleton Papers Inc. (US) 2006-03-08 EP disclosed
WO-2004106168-A2 LINERLESS LABELS APPLETON PAPERS INC. (US) 2004-12-09 WO disclosed
US-20040234756-A1 Linerless labels APPLETON PAPERS INC. 2004-11-25 US disclosed
EP-0550140-B1 Mono(indolylethylenyl)Phthalides APPLETON PAPER INC (US) 1995-09-20 EP disclosed
EP-0550140-A1 Mono(indolylethylenyl)Phthalides APPLETON PAPERS INC. (US) 1993-07-07 EP disclosed
US-5218127-A Condensing indolylyethylene with keto acid and electron acceptor in presence of organic solvent APPLETON PAPERS INC. (US) 1993-06-08 US disclosed
US-5200519-A Chromogens for pressure sensitive and thermal recording systems APPLETON PAPERS INC. (US) 1993-04-06 US disclosed