SCHEMBL7482195

SCHEMBL7482195

CCN(CC)c1ccc(C2(/C=C(\c3ccc(OC)cc3)c3c(C)n(CC)c4ccccc34)OC(=O)c3ccccc32)cc1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.39
CNR2 P34972 3/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GRIK2 Q13002 1/20 0.34
MAPT P10636 1/20 0.33
TSPO P30536 1/20 0.33
BACE1 P56817 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7477653 0.92 MEN1 (0.34) CNR1CNR2KDM4EMEN1NPC1
SCHEMBL7479433 0.92 SRD5A1 (0.33) CNR1CNR2KDM4EMEN1RAB9A
SCHEMBL7482470 0.91 SRD5A1 (0.32) CNR1CNR2MEN1NPC1RAB9A
SCHEMBL7482121 0.91 SRD5A1 (0.39) CNR1CNR2KDM4EMAPK1HTT
SCHEMBL29386399 0.90 ALDH1A1 (0.34) CNR1CNR2KDM4EMEN1RAB9A
SCHEMBL25608 0.90 ALDH1A1 (0.34) CNR1CNR2KDM4EMEN1RAB9A
SCHEMBL5508192 0.89 KDM4E (0.46) CNR2KDM4EMEN1NPC1RAB9A
SCHEMBL7483499 0.87 MAPT (0.34) CNR1CNR2KDM4EMEN1KMT2A
SCHEMBL7477171 0.86 CNR2 (0.32) CNR1CNR2KDM4EMEN1RAB9A
SCHEMBL7481955 0.85 MEN1 (0.33) CNR1CNR2KDM4EMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0664292-B1 A phtalide compound and a near infrared absorber and a recording material each comprising the same compound YAMAMOTO CHEMICALS INC (JP) 2002-06-19 EP disclosed
US-5627287-A COLORLESS YAMAMOTO CHEMICALS, INC. (JP) 1997-05-06 US disclosed
EP-0664292-A1 A phtalide compound and a near infrared absorber and a recording material each comprising the same compound YAMAMOTO CHEMICALS, INC. (JP) 1995-07-26 EP disclosed