Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5433395 | 0.78 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL3694128 | 0.74 | HTR1A (0.32) | — | |
| SCHEMBL1267174 | 0.71 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL5653235 | 0.70 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL5436007 | 0.70 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL2539639 | 0.69 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL2540548 | 0.69 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL5315333 | 0.69 | MTNR1A (0.30) | — | |
| SCHEMBL5254382 | 0.69 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL5317187 | 0.69 | KCNH2 (0.32) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799676-A2 | NEW BICYCLIC ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006032466-A2 | NEW BICYCLIC ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-03-30 | — | — | WO | disclosed |