Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2918963 | 1.00 | LMNA (0.34) | LMNAALDH1A1SMN1; SMN2PKMNPC1 | |
| SCHEMBL2924916 | 1.00 | LMNA (0.34) | LMNAALDH1A1SMN1; SMN2PKMNPC1 | |
| SCHEMBL2916700 | 0.94 | LMNA (0.33) | LMNAALDH1A1SMN1; SMN2PKMNPC1 | |
| SCHEMBL2944665 | 0.94 | RORC (0.36) | LMNAALDH1A1SMN1; SMN2PKMNPC1 | |
| SCHEMBL2919072 | 0.94 | RORC (0.36) | LMNAALDH1A1SMN1; SMN2PKMNPC1 | |
| SCHEMBL2919069 | 0.94 | RORC (0.36) | LMNAALDH1A1SMN1; SMN2PKMNPC1 | |
| SCHEMBL2919684 | 0.94 | RORC (0.36) | LMNAALDH1A1SMN1; SMN2PKMNPC1 | |
| SCHEMBL2920634 | 0.94 | RORC (0.36) | LMNAALDH1A1SMN1; SMN2PKMNPC1 | |
| SCHEMBL2920447 | 0.94 | RORC (0.36) | LMNAALDH1A1SMN1; SMN2PKMNPC1 | |
| SCHEMBL2924064 | 0.94 | RORC (0.36) | LMNAALDH1A1SMN1; SMN2PKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863803-A2 | SUBSTITUTED PIPERIDINES | Speedel Experimenta AG (CH) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006103277-A2 | 2 , 4 , 5-SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS | SPEEDEL EXPERIMENTA AG (CH) | 2006-10-05 | — | — | WO | disclosed |