SCHEMBL5508797

SCHEMBL5508797

CNc1ccc(F)c2c(NC)c(F)ccc12

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.34
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
KMT2A Q03164 1/20 0.34
KEAP1 Q14145 1/20 0.34
NFE2L2 Q16236 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5520161 0.83 MEN1 (0.32) IDO1MEN1USP2KMT2AKEAP1
SCHEMBL5508271 0.78 CRHBP (0.31) MEN1USP2KMT2AKEAP1NFE2L2
SCHEMBL5512543 0.78 IDO1 (0.41) IDO1MEN1USP2KMT2AKEAP1
SCHEMBL5522909 0.76 MEN1 (0.45) IDO1MEN1USP2KMT2AKEAP1
SCHEMBL5512067 0.75 USP2 (0.33) IDO1MEN1USP2KMT2AKEAP1
SCHEMBL5511625 0.75 ADRA2A (0.31)
SCHEMBL5511146 0.74 IDO1 (0.41) IDO1MEN1USP2KMT2AKEAP1
SCHEMBL5513312 0.74 BRAF (0.32) IDO1
SCHEMBL5513296 0.74 MAP2K1 (0.33) IDO1KMT2A
SCHEMBL5511699 0.72 TSHR (0.38) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208559-B2 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2007-04-24 US disclosed
US-20060135712-A1 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2006-06-22 US disclosed